Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136288 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1CASRADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11134351 | 0.99 | ADRB2 (0.54) | ADRB2ADRB1CASR | |
| SCHEMBL11129792 | 0.85 | ADRB2 (0.45) | ADRB2ADRB1CASR | |
| SCHEMBL11122771 | 0.85 | ADRB2 (0.45) | ADRB2ADRB1CASR | |
| Hydrochloric Acid SCHEMBL8855378 | 0.84 | ADRB2 (0.44) | ADRB2ADRB1CASR | |
| SCHEMBL11132431 | 0.82 | ADRB2 (0.51) | ADRB2ADRB1CASR | |
| SCHEMBL11137221 | 0.82 | ADRB2 (0.51) | ADRB2ADRB1CASR | |
| SCHEMBL4626574 | 0.81 | ADRB1 (0.49) | ADRB2ADRB1ADRA2AADRA2BADRA2C | |
| Hydrochloric Acid SCHEMBL11134717 | 0.81 | ADRB2 (0.53) | ADRB2ADRB1CASR | |
| Bromide SCHEMBL11135620 | 0.81 | ADRB2 (0.50) | ADRB2ADRB1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007206-B1 | PHENETHANOLAMINES, THEIR FORMULATIONS, PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 1983-02-23 | — | — | EP | disclosed |
| EP-0007206-A1 | Phenethanolamines, their formulations, preparation and use | ELI LILLY AND COMPANY (US) | 1980-01-23 | — | — | EP | disclosed |