Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694634 | 0.92 | PRSS1 (0.47) | NPC1RAB9APRSS1TPSAB1ALDH1A1 | |
| SCHEMBL24062673 | 0.84 | PRSS1 (0.47) | MMP2MMP12MMP1MMP9NPC1 | |
| Benzyl Dimethylcarbamate SCHEMBL20401678 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1HPGD | |
| Benzyl Dimethylcarbamate SCHEMBL5134244 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1HPGD | |
| Benzyl Dimethylcarbamate SCHEMBL14031385 | 0.82 | ALDH1A1 (0.62) | ALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL28886931 | 0.81 | ALDH1A1 (0.51) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL15601806 | 0.81 | PRSS1 (0.51) | MMP2MMP12MMP1MMP9NPC1 | |
| SCHEMBL24591903 | 0.81 | MMP2 (0.47) | MMP2MMP12MMP1MMP9NPC1 | |
| SCHEMBL19389590 | 0.80 | PRSS1 (0.43) | NPC1RAB9APRSS1TPSAB1ALDH1A1 | |
| SCHEMBL24491208 | 0.80 | PRSS1 (0.53) | MMP2MMP12MMP1MMP9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58032859-A | — | — | None | — | — | JP | disclosed |
| JP-S5832859-A | N,N-DIMETHYLCARBAMIC ACID BENZYL ESTER DERIVATIVE | DAINIPPON PHARMACEUT CO LTD | 1983-02-25 | — | — | JP | disclosed |