Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6291619 | 0.78 | MAPT (0.51) | MAPTMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL17991053 | 0.78 | MEN1 (0.50) | MAPTCYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL11571020 | 0.76 | CYP2D6 (0.59) | CYP2D6ADRB2ADRB1ADRB3 | |
| Butyric Acid SCHEMBL28199511 | 0.75 | TSHR (0.51) | MAPTCYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL267463 | 0.74 | LMNA (0.68) | MAPTCYP2D6ADRB2ADRB1ADRB3 | |
| Methacrylic Acid SCHEMBL28914843 | 0.74 | LMNA (0.57) | MAPTMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL6351413 | 0.74 | MAPT (0.57) | MAPTMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL3857282 | 0.74 | ALOX5 (0.51) | MAPTMTNR1AMTNR1BPOLBL3MBTL1 | |
| SCHEMBL9661011 | 0.72 | MAPT (0.78) | MAPTCYP2D6ADRB2ADRB1ADRB3 | |
| SCHEMBL27927295 | 0.72 | MAPT (0.51) | MAPTMTNR1AMTNR1BCYP2D6ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4404384-A | HYPOTENSIVE, ANTISPASMODIC, CHOLERETIC AGENTS; ANTICONUULSANTS; ANTIPYRETICS; ANTHELMINTICS; FUNGICIDWS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-13 | — | — | US | disclosed |