Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653336 | 0.86 | FNTA (0.49) | PTPN1LTA4HSMN1; SMN2LMNAFNTA | |
| SCHEMBL10655585 | 0.86 | FNTA (0.49) | PTPN1LTA4HSMN1; SMN2LMNAFNTA | |
| SCHEMBL11455957 | 0.85 | PTPN1 (0.44) | PTPN1LTA4HLMNAFNTAFNTB | |
| SCHEMBL10654417 | 0.84 | LMNA (0.47) | PTPN1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL10657996 | 0.84 | LMNA (0.47) | PTPN1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL10657196 | 0.83 | LMNA (0.48) | PTPN1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL10653360 | 0.83 | LMNA (0.48) | PTPN1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL11446573 | 0.82 | LMNA (0.46) | PTPN1LTA4HLMNAFNTAFNTB | |
| Ambamustine SCHEMBL62822 | 0.77 | LMNA (0.41) | PTPN1SMN1; SMN2LMNAFNTAFNTB | |
| SCHEMBL11129156 | 0.77 | HTT (0.39) | PTPN1SMN1; SMN2LMNAFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0056565-B1 | DERIVATIVES OF DI(-2-CHLOROETHYL) AMINOPHENYL ALANINE WITH ANTITUMOUR ACTIVITY | PROTER S.p.A. (IT) | 1984-12-05 | — | — | EP | claimed |