SCHEMBL11136124

SCHEMBL11136124

CN1CCC(=O)C12C(=O)C2=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.32
BRD2 P25440 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3306349 0.72
SCHEMBL4743786 0.68 BRD4 (0.31) BRD4BRD2
SCHEMBL11352477 0.64
SCHEMBL11729133 0.61 ATM (0.36) BRD4BRD2
SCHEMBL11728651 0.59 BRD4 (0.36) BRD4BRD2
SCHEMBL6806461 0.59 RAB9A (0.31) BRD4BRD2
SCHEMBL17382112 0.59 BRD4 (0.31) BRD4BRD2
SCHEMBL25041109 0.57 ACHE (0.30) BRD4BRD2
SCHEMBL14070456 0.57 CRBN (0.36) BRD4BRD2
SCHEMBL25465746 0.57 CHRM2 (0.32) BRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4400489-A A FATTY ACID-MODIFIED COPOLYMER OF AN EPOXY-CONTAINING ACRYLIC ESTER AS BINDER AND A DICARBONYL; LACQUERS BAYER AKTIENGESELLSCHAFT (DE) 1983-08-23 US claimed
US-4400489-A A FATTY ACID-MODIFIED COPOLYMER OF AN EPOXY-CONTAINING ACRYLIC ESTER AS BINDER AND A DICARBONYL; LACQUERS BAYER AKTIENGESELLSCHAFT (DE) 1983-08-23 US disclosed
EP-0053740-A1 Air-curable polyacrylate coatings BAYER AG (DE) 1982-06-16 EP disclosed