Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | ACR | P10323 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315797 | 0.88 | MAPT (0.56) | MAPTTDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11136274 | 0.86 | MAPT (0.54) | MAPTTDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11581875 | 0.85 | MAPT (0.50) | HTTMAPTTDP1KMT2AMEN1 | |
| SCHEMBL11142712 | 0.85 | MAPT (0.50) | HTTMAPTTDP1KMT2AMEN1 | |
| SCHEMBL11581069 | 0.85 | MAPT (0.53) | HTTMAPTTDP1KMT2AMEN1 | |
| SCHEMBL11143238 | 0.85 | MAPT (0.55) | MAPTTDP1KMT2ASRD5A1ALDH1A1 | |
| SCHEMBL11140597 | 0.84 | MAPT (0.56) | MAPTTDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11140786 | 0.84 | HTT (0.56) | HTTMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11582375 | 0.84 | KDM4E (0.49) | MAPTTDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11584793 | 0.82 | MAPT (0.57) | MAPTTDP1KMT2AMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4392999-A | COLORFAST BROWN, RED AND ORANGE | CIBA-GEIGY CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4229344-A | Monazo pigments containing hydroxynaphthoylaminobenzimidazalone radical | CIBA-GEIGY CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |