Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | ACR | P10323 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143238 | 0.89 | MAPT (0.55) | MAPTTDP1PRSS1ACRLMNA | |
| SCHEMBL11315797 | 0.89 | MAPT (0.56) | MAPTTDP1PRSS1ACRCYP2C9 | |
| SCHEMBL11581069 | 0.86 | MAPT (0.53) | MAPTTDP1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL11136239 | 0.86 | HTT (0.54) | MAPTTDP1PRSS1ACRCYP2C9 | |
| SCHEMBL11140597 | 0.86 | MAPT (0.56) | MAPTTDP1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL11142542 | 0.84 | ALDH1A1 (0.63) | MAPTPRSS1ACRCYP2C9CYP1A2 | |
| SCHEMBL11182852 | 0.84 | PRSS1 (0.58) | MAPTTDP1PRSS1ACRCYP1A2 | |
| SCHEMBL11584793 | 0.84 | MAPT (0.57) | MAPTTDP1CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL11581046 | 0.84 | MAPT (0.57) | MAPTTDP1PRSS1ACRSMN1; SMN2 | |
| SCHEMBL11582919 | 0.83 | MAPT (0.56) | MAPTTDP1PRSS1ACRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4392999-A | COLORFAST BROWN, RED AND ORANGE | CIBA-GEIGY CORPORATION (US) | 1983-07-12 | — | — | US | disclosed |
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4229344-A | Monazo pigments containing hydroxynaphthoylaminobenzimidazalone radical | CIBA-GEIGY CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4070353-A | FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |