Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | ACR | P10323 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315797 | 0.88 | MAPT (0.56) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11136274 | 0.86 | MAPT (0.54) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11143238 | 0.85 | MAPT (0.55) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11136239 | 0.85 | HTT (0.54) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11140597 | 0.84 | MAPT (0.56) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11584793 | 0.82 | MAPT (0.57) | MAPTTDP1KMT2AMEN1LMNA | |
| SCHEMBL11581046 | 0.82 | MAPT (0.57) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11182852 | 0.82 | PRSS1 (0.58) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11582919 | 0.81 | MAPT (0.56) | MAPTTDP1KMT2APRSS1ACR | |
| SCHEMBL11143347 | 0.81 | MAPT (0.53) | MAPTTDP1KMT2APRSS1ACR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070353-A | FOR PLASTICS AND PRINTING INKS, YELLOW TO ORANGE SHADES | CIBA-GEIGY CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |