SCHEMBL11136244

SCHEMBL11136244

COC(C)(C)CCC[C](C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11232780 0.81 ALDH1A1 (0.39) ALDH1A1TDP1TSHRLMNACYP3A4
SCHEMBL10639638 0.78 ALDH1A1 (0.31) ALDH1A1TDP1LMNACYP3A4
SCHEMBL10639634 0.78 ALDH1A1 (0.31) ALDH1A1TDP1LMNACYP3A4
SCHEMBL984967 0.76 TSHR (0.46) ALDH1A1TDP1TSHRLMNA
SCHEMBL31214626 0.75 TSHR (0.58) ALDH1A1TSHRLMNA
SCHEMBL10967647 0.74 CYP3A4 (0.41) ALDH1A1TDP1TSHRLMNACYP3A4
SCHEMBL10967643 0.74 CYP3A4 (0.41) ALDH1A1TDP1TSHRLMNACYP3A4
SCHEMBL7876257 0.74 ALDH1A1 (0.41) ALDH1A1TDP1TSHR
SCHEMBL7808732 0.74
SCHEMBL9609529 0.73 ALDH1A1 (0.41) ALDH1A1TDP1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0030109-B1 PROCESS FOR PRODUCING ISOPRENE KURARAY CO., LTD. (JP) 1983-10-05 EP disclosed
US-4381416-A Process for producing isoprene KURARAY CO., LTD. (JP) 1983-04-26 US disclosed
EP-0030109-A1 Process for producing isoprene KURARAY CO., LTD. (JP) 1981-06-10 EP disclosed