Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136276 | 0.92 | APEX1 (0.55) | APEX1KMT2AMEN1GAAPOLB | |
| SCHEMBL11514077 | 0.90 | RAB9A (0.44) | APEX1KMT2AMEN1GAAPOLB | |
| SCHEMBL11433142 | 0.88 | APEX1 (0.56) | APEX1KMT2AMEN1GAAPOLB | |
| SCHEMBL11433134 | 0.88 | APEX1 (0.55) | APEX1KMT2AMEN1GAAPOLB | |
| SCHEMBL8755454 | 0.86 | APEX1 (0.70) | APEX1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL11587244 | 0.84 | TIMP3 (0.46) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11444026 | 0.84 | TIMP3 (0.46) | KMT2AMEN1GAAPOLBMAPT | |
| SCHEMBL11137430 | 0.83 | APEX1 (0.55) | APEX1KMT2AMEN1GAAPOLB | |
| SCHEMBL11135640 | 0.83 | APEX1 (0.59) | APEX1KMT2AMEN1GAAMAPT | |
| SCHEMBL11589837 | 0.83 | APEX1 (0.59) | APEX1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4103028-A | SUBSTITUTED HYDROXY NAPHTHALENEDISULFONIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1978-07-25 | — | — | US | claimed |
| US-4391824-A | INHIBITING CONNECTIVE TISSUE DISTRUCTION, ENZYME INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1983-07-05 | — | — | US | disclosed |
| US-4127602-A | Methyl substituted hydroxynaphthalenesulfonic acid ureides and salts as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4103028-A | SUBSTITUTED HYDROXY NAPHTHALENEDISULFONIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4046805-A | Substituted-hydroxy-naphthalenedisulfonic acid compounds | AMERICAN CYANAMID COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-4018764-A | IMMUNOLOGY, ANTIBODY INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1977-04-19 | — | — | US | disclosed |