Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116252 | 0.86 | HDAC8 (0.48) | HDAC8MMP3PLK1NR1H4SCN5A | |
| SCHEMBL2323089 | 0.85 | PLK1 (0.51) | HDAC8MMP3PLK1SCN5ASCN2A | |
| SCHEMBL4131145 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7294000 | 0.80 | HDAC8 (0.47) | HDAC8MMP3PLK1SCN5ASCN2A | |
| SCHEMBL8013551 | 0.77 | ALDH1A1 (0.49) | HDAC8ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27295439 | 0.77 | KDM4E (0.57) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL27295441 | 0.77 | KDM4E (0.57) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL1605906 | 0.77 | HDAC8 (0.74) | HDAC8MMP3PLK1ALDH1A1KDM4E | |
| SCHEMBL14861047 | 0.76 | SCN5A (0.44) | HDAC8MMP3PLK1SCN5ASCN2A | |
| SCHEMBL8405220 | 0.76 | LTA4H (0.49) | HDAC8MMP3PLK1NR1H4SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4372941-A | FOR PRESENCE OF HYDROLYTIC ENZYMES | UNIVERSITY OF MIAMI | 1983-02-08 | — | — | US | disclosed |