Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058402 | 0.94 | LMNA (0.53) | LMNAEPHX1ALDH1A1CYP3A4TAS2R38 | |
| SCHEMBL11054397 | 0.89 | LMNA (0.51) | LMNAALDH1A1CYP3A4ALOX12CYP1A2 | |
| SCHEMBL11280096 | 0.87 | POLB (0.44) | LMNAALDH1A1CYP3A4ALOX12CYP1A2 | |
| SCHEMBL20026950 | 0.83 | LMNA (0.72) | LMNAALDH1A1CYP3A4TAS2R38HSD17B10 | |
| SCHEMBL11138510 | 0.82 | LMNA (0.45) | LMNAALDH1A1CYP3A4ALOX12CYP1A2 | |
| SCHEMBL11142824 | 0.81 | ALOX12 (0.61) | LMNAALDH1A1CYP3A4ALOX12CYP1A2 | |
| SCHEMBL11139014 | 0.81 | HTT (0.50) | LMNAEPHX1ALDH1A1CYP3A4TAS2R38 | |
| SCHEMBL11053555 | 0.80 | ALOX12 (0.60) | LMNAALDH1A1CYP3A4ALOX12CYP1A2 | |
| SCHEMBL11284346 | 0.79 | POLB (0.47) | LMNAALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL11058243 | 0.79 | LMNA (0.49) | LMNAALDH1A1CYP3A4ALOX12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418209-A | ANTIULCER, ANTIARRYTHMIC, ANTIDIARRHEAL, ANTISPASMODIC, ANTIPARASITIC, AND ANTISECRETORY AGENTS | WILLIAM H. RORER, INC. (US) | 1983-11-29 | — | — | US | disclosed |