Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 12/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142054 | 0.87 | OPRD1 (0.52) | OPRD1OPRM1OPRK1 | |
| Enkephalin SCHEMBL30857 | 0.87 | OPRD1 (0.75) | OPRD1OPRM1OPRK1 | |
| Enkephalin SCHEMBL631959 | 0.87 | OPRD1 (0.75) | OPRD1OPRM1OPRK1 | |
| Enkephalin SCHEMBL16189980 | 0.87 | OPRD1 (0.75) | OPRD1OPRM1OPRK1 | |
| Enkephalin SCHEMBL631958 | 0.87 | OPRD1 (0.75) | OPRD1OPRM1OPRK1 | |
| Enkephalin SCHEMBL11399380 | 0.87 | OPRD1 (0.75) | OPRD1OPRM1OPRK1 | |
| SCHEMBL29355873 | 0.87 | OPRD1 (0.73) | OPRD1OPRM1OPRK1 | |
| SCHEMBL31222367 | 0.87 | FOLH1 (0.51) | OPRD1OPRM1 | |
| SCHEMBL31222371 | 0.87 | FOLH1 (0.51) | OPRD1OPRM1 | |
| Enkephalin SCHEMBL25236888 | 0.87 | OPRD1 (0.73) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371463-A | Enzyme-resistant opiate pentapeptides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1983-02-01 | — | — | US | claimed |
| US-4028319-A | 2 AND 3-SUBSTITUTED ENKEPHALINS | G. D. SEARLE & CO. (US) | 1977-06-07 | — | — | US | claimed |
| US-4028319-A | 2 AND 3-SUBSTITUTED ENKEPHALINS | G. D. SEARLE & CO. (US) | 1977-06-07 | — | — | US | disclosed |