Enkephalin

Enkephalin

SCHEMBL631958

CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 11/20 0.75
OPRM1 P35372 7/20 0.72
OPRK1 P41145 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Enkephalin SCHEMBL631959 1.00 OPRD1 (0.75) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL11399380 1.00 OPRD1 (0.75) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL16189980 1.00 OPRD1 (0.75) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL30857 1.00 OPRD1 (0.75) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL25236888 0.99 OPRD1 (0.73) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL30400052 0.99 OPRD1 (0.73) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL29458101 0.98 OPRD1 (0.72) OPRD1OPRM1OPRK1
SCHEMBL29355873 0.98 OPRD1 (0.73) OPRD1OPRM1OPRK1
Enkephalin SCHEMBL8580265 0.95 OPRD1 (0.75) OPRD1OPRM1OPRK1
SCHEMBL8077732 0.94 OPRD1 (0.73) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 466 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260027062-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS CYPRUMED GMBH (AT) 2026-01-29 US claimed
US-20260001910-A1 PEPTIDES AND USES THEREOF PREVECEUTICAL MEDICAL INC (CA) 2026-01-01 US claimed
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2025-11-13 US claimed
US-12399186-B2 Method for diagnosing or monitoring kidney function or diagnosing kidney dysfunction SPHINGOTEC GMBH (DE) 2025-08-26 US claimed
EP-4603151-A1 STABLE COSMETIC COMPOSITION, METHODS AND USES THEREOF Solfarcos Soluções Farmaceuticas e Cosmeticas Lda (PT) 2025-08-20 EP claimed
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP claimed
CN-113421620-B Based on UPLC-Q-TOF/MSEMethod for carrying out fuzzy recognition on bioactive components with different effects of traditional Chinese medicine by BP neural network correlation analysis of integration effect 陕西中医药大学 2025-04-29 CN claimed
CN-119403786-A Bifunctional molecules that selectively induce degradation of extracellular targets in lysosomes 德罗普尼尔生物有限公司 2025-02-07 CN claimed
US-12208118-B2 Pharmaceutical compositions for delivery of peptide ANYA BIOPHARM INC. (CN) 2025-01-28 US claimed
EP-4486366-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS Cyprumed GmbH (AT) 2025-01-08 EP claimed
WO-2023285412-A1 IMPROVED SUBSTANCE QUANTIFICATION IN COMPLEX MIXTURES ISA PHARMACEUTICALS B.V. (NL) 2023-01-19 WO claimed
US-20220347184-A1 SKIN-PENETRATING FORMULATION OF TAUROLIDINE CORMEDIX INC (US) 2022-11-03 US claimed
US-20220288111-A1 PHARMACEUTICAL COMPOSITIONS FOR DELIVERY OF PEPTIDE ANYA BIOPHARM INC. (CN) 2022-09-15 US claimed
CN-111812246-B Method for tracking blood-entering components of five-flavor warmth-dredging and arthralgia-removing capsule and targeting quality marker 安徽中医药大学第一附属医院(安徽省中医院) 2022-06-10 CN claimed
CN-114414673-A Method for identifying vegetable oil types 哈尔滨医科大学 2022-04-29 CN claimed
CN-114414671-A Research method for metabolic pathway of diabetes differential metabolites by using coreopsis bicolor 天津中医药大学 2022-04-29 CN claimed
CN-114235979-A Marine microorganism lipid ion mobility mass spectrometry method and application 南方科技大学 2022-03-25 CN claimed
CN-114137226-A Marker for early diagnosis of cerebral infarction, screening method and application thereof, and construction method and application of model for early diagnosis of cerebral infarction 首都师范大学 2022-03-04 CN claimed
CN-114062473-A Method for evaluating storage quality of dried sea cucumbers based on iKnife evaporation ionization mass spectrometry 浙江工商大学 2022-02-18 CN claimed
CN-113968902-A Leucine-enkephalin analogue and preparation method and application thereof 兰州大学 2022-01-25 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES SORT1, SCARB1, LAMP1 OPRD1 3942/4885OPRM1 3885/4885OPRK1 4105/4885
US-20260027062-A1 IMPROVED ORAL PHARMACEUTICAL FORMULATIONS OF THERAPEUTIC PEPTIDES AND PROTEINS ADM2, TAS2R42, ACP1 OPRD1 1918/4885OPRM1 865/4885OPRK1 3676/4885
US-20260001910-A1 PEPTIDES AND USES THEREOF MMP3, PEPD, MMP9 OPRD1 722/4885OPRM1 744/4885OPRK1 1641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.