SCHEMBL11136702

SCHEMBL11136702

Cc1c(S(=O)(=O)O)ccc(Cl)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 6/20 0.36
RECQL P46063 2/20 0.36
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
THRB P10828 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TTR P02766 1/20 0.35
SUMO2 P61956 2/20 0.35
SUMO1 P63165 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
SENP2 Q9HC62 2/20 0.35
SENP1 Q9P0U3 2/20 0.35
SENP3 Q9H4L4 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11235101 0.85 ALDH1A1 (0.36) MEN1KMT2ACYP2C9ALDH1A1RECQL
SCHEMBL27492603 0.82 KMT2A (0.38) MEN1KMT2AALDH1A1RECQLTSHR
SCHEMBL8082214 0.80 AURKA (0.43) MEN1KMT2ACYP2C9ALDH1A1RECQL
SCHEMBL9449070 0.80 ALDH1A1 (0.38) MEN1KMT2ACYP2C9ALDH1A1RECQL
SCHEMBL8752158 0.80 MEN1 (0.47) MEN1KMT2ACYP2C9ALDH1A1RECQL
SCHEMBL10698298 0.78 AURKA (0.39) MEN1KMT2ACYP2C9ALDH1A1RECQL
SCHEMBL9768977 0.77 CA2 (0.42) MEN1KMT2ACYP2C9ALDH1A1TSHR
SCHEMBL11820472 0.77 CYP2C9 (0.36) MEN1KMT2ACYP2C9ALDH1A1RECQL
SCHEMBL28139282 0.77 AURKA (0.41) MEN1KMT2ACYP2C9ALDH1A1RECQL
SCHEMBL10589831 0.76 MEN1 (0.44) MEN1KMT2AALDH1A1RECQLTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4399068-A Concentrated, aqueous solutions of salts of acetoacetylamino-arylsulphonic acids and method of forming concentrated solutions of azo dyestuffs therefrom BAYER AKTIENGESELLSCHAFT (DE) 1983-08-16 US disclosed