Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9784525 | 0.89 | HDAC6 (0.61) | EPHX1ALDH1A1EGFRMEN1KMT2A | |
| SCHEMBL10891269 | 0.87 | CA12 (0.57) | EPHX1CA12CA1CA9CA2 | |
| SCHEMBL11136802 | 0.85 | EGFR (0.48) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL11643923 | 0.85 | CA12 (0.61) | EPHX1CA12CA1CA9CA2 | |
| SCHEMBL10886552 | 0.84 | UBE2M (0.56) | EPHX1CA12CA1CA9CA2 | |
| SCHEMBL11135753 | 0.84 | CA12 (0.60) | CA12CA1CA9CA2HPGD | |
| SCHEMBL11132924 | 0.83 | CA12 (0.58) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL2448810 | 0.82 | HDAC6 (0.65) | EPHX1CA12CA1CA9CA2 | |
| SCHEMBL11138778 | 0.81 | APEX1 (0.60) | EPHX1CA12CA1CA9CA2 | |
| SCHEMBL11132349 | 0.81 | CCKBR (0.56) | CA12CA1CA9CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387105-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY | 1983-06-07 | — | — | US | claimed |
| US-4387105-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY | 1983-06-07 | — | — | US | disclosed |