Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.70 |
| ▸ | MEN1 | O00255 | 11/20 | 0.69 |
| ▸ | MAPT | P10636 | 9/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139020 | 0.91 | CSNK2A1 (0.66) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11140681 | 0.87 | TYR (0.58) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11137393 | 0.84 | HPGDS (0.64) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11134270 | 0.83 | KMT2A (0.53) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11144373 | 0.81 | KMT2A (0.61) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11137982 | 0.81 | MEN1 (0.70) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11138002 | 0.81 | MEN1 (0.77) | KMT2AMEN1MAPTNPC1LMNA | |
| SCHEMBL5046651 | 0.80 | KMT2A (0.80) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL11137552 | 0.80 | ALDH1A1 (0.78) | KMT2AMEN1MAPTSMN1; SMN2HTT | |
| SCHEMBL16607144 | 0.79 | KMT2A (0.78) | KMT2AMEN1MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4407810-A | TREATMENT OF ALLERGIC DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1983-10-04 | — | — | US | disclosed |
| EP-0044442-A1 | N-(4-Phenyl-2-thiazolyl)-oxamidic-acid-2-ethoxyethylester, process for its preparation and pharmaceutical compositions containing this compound | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |
| US-4238496-A | ANTIALLERGENS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-12-09 | — | — | US | disclosed |