Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 4/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138401 | 0.99 | MAPK1 (0.63) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL30530511 | 0.93 | MAPK1 (0.70) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL97551 | 0.93 | MAPK1 (0.70) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL4313671 | 0.87 | HPGD (0.68) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL27780501 | 0.85 | MAPK1 (0.61) | MAPK1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL11137640 | 0.85 | LMNA (0.58) | MAPK1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL11132570 | 0.83 | LMNA (0.56) | MAPK1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL30947438 | 0.82 | LMNA (0.78) | MAPK1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL10540636 | 0.81 | LMNA (0.57) | MAPK1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL97994 | 0.80 | LMNA (0.62) | MAPK1KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4377695-A | ANTIINFLAMMATORY, ANALGESIC, ANTICOAGULANT AGENTS | A. NATTERMANN & CIE GMBH (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0051827-A1 | Omega-(2-oxo-benzimidazolinyl)-alkanoic acid derivatives, process for producing the same and pharmaceutical compounds containing the same | A. Nattermann & Cie. GmbH (DE) | 1982-05-19 | — | — | EP | disclosed |