Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 5/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30530511 | 0.87 | MAPK1 (0.70) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL97551 | 0.87 | MAPK1 (0.70) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL133515 | 0.85 | LMNA (0.58) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL30947438 | 0.84 | LMNA (0.78) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL14664243 | 0.84 | LMNA (0.61) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL27780501 | 0.82 | MAPK1 (0.61) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL11514674 | 0.82 | LMNA (0.58) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL13240512 | 0.82 | LMNA (0.58) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL30277537 | 0.81 | LMNA (0.69) | LMNAMAPK1HTTHPGDALDH1A1 | |
| SCHEMBL318787 | 0.81 | LMNA (0.69) | LMNAMAPK1HTTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2142553-B1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INT BV (NL) | 2015-08-19 | — | — | EP | claimed |
| EP-3190114-B1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | INTERVET INT BV (NL) | 2019-11-06 | — | — | EP | disclosed |
| EP-2935275-B9 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-10-11 | — | — | EP | disclosed |
| EP-3190114-A1 | PROCESS FOR MAKING A CRYSTALLINE ZILPATEROL SALT | Intervet International B.V. (NL) | 2017-07-12 | — | — | EP | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| US-9630967-B2 | Process for making zilpaterol | INTERVET INC. (US) | 2017-04-25 | — | — | US | disclosed |
| EP-2935275-B1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INT BV (NL) | 2017-03-08 | — | — | EP | disclosed |
| EP-2535340-B1 | Process for making zilpaterol and salts thereof | INTERVET INT BV (NL) | 2016-04-27 | — | — | EP | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | INTERVET INC. (US) | 2015-11-05 | — | — | US | disclosed |
| US-20100121050-A1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2010-05-13 | — | — | US | disclosed |
| US-20080267942-A1 | BENZAZEPIN-2(1H)-ONE DERIVATIVES | PFIZER LIMITED (GB) | 2008-10-30 | — | — | US | disclosed |
| US-20080267942-A1 | BENZAZEPIN-2(1H)-ONE DERIVATIVES | PFIZER LIMITED (GB) | 2008-10-30 | — | — | US | disclosed |
| WO-2008119754-A1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | INTERVET INTERNATIONAL B.V. (NL) | 2008-10-09 | — | — | WO | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
| US-20080161288-A1 | COMPOUNDS | PFIZER INC. | 2008-07-03 | — | — | US | disclosed |
| WO-2008050207-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LIMITED (GB) | 2008-05-02 | — | — | WO | disclosed |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | PFIZER LIMITED (GB) | 2008-05-01 | — | — | US | disclosed |
| WO-2008044127-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS ANABOLIC AGENTS FOR LIVESTOCK ANIMALS | PFIZER LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103130-A1 | 7-hydroxy-6-{[1-methyl-3-(1,3-thiazol-5-yl)propyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one; agonists at the beta-2 adrenoceptor; feed additives for livestock animals; improving meat yield or meat quality | ADRB2, ADRB1, ADRA2C | LMNA 999/4885MAPK1 1646/4885HTT 2508/4885 |
| US-20100121050-A1 | PROCESSES FOR MAKING ZILPATEROL AND SALTS THEREOF | SLC39A11, SLC39A3, ZFR | LMNA 1307/4885MAPK1 2812/4885HTT 2296/4885 |
| US-20080161288-A1 | COMPOUNDS | ADRB2, ADRB1, ADRA2C | LMNA 1543/4885MAPK1 2370/4885HTT 3868/4885 |
| US-20080267942-A1 | BENZAZEPIN-2(1H)-ONE DERIVATIVES | ADRB2, ADRB1, ADRA2C | LMNA 865/4885MAPK1 2354/4885HTT 4559/4885 |
| US-20150315195-A1 | AN IMPROVED PROCESS FOR MAKING ZILPATEROL | PPIP5K2, PPIA, ITPA | LMNA 2499/4885MAPK1 4440/4885HTT 2864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.