Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 11/20 | 0.50 |
| ▸ | GRM3 | Q14832 | 8/20 | 0.50 |
| ▸ | GRM6 | O15303 | 8/20 | 0.50 |
| ▸ | GRM8 | O00222 | 4/20 | 0.50 |
| ▸ | GRM5 | P41594 | 5/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13319983 | 0.72 | GRM2 (0.53) | GRM2GRM3GRM6GRM8GRM5 | |
| SCHEMBL7752047 | 0.71 | GRM2 (0.47) | GRM2GRM3GRM6GRM8GRM5 | |
| SCHEMBL2939527 | 0.69 | GRM2 (0.46) | GRM2GRM3GRM6GRM8GRM5 | |
| SCHEMBL7135246 | 0.69 | GRM2 (0.46) | GRM2GRM3GRM6GRM8GRM5 | |
| SCHEMBL27595459 | 0.69 | GRM4 (0.76) | GRM2GRM3GRM6GRM8GRM5 | |
| SCHEMBL28434000 | 0.68 | GRM2 (0.44) | GRM2GRM3GRM6GRM8GRM5 | |
| SCHEMBL27691317 | 0.68 | GRM4 (0.56) | GRM2GRM3GRM6GRM8GRM5 | |
| Eglumetad SCHEMBL13728495 | 0.67 | GRM2 (1.00) | GRM2GRM3GRM6GRM8GRM4 | |
| Eglumetad SCHEMBL481248 | 0.67 | GRM2 (1.00) | GRM2GRM3GRM6GRM8GRM4 | |
| Eglumetad SCHEMBL15060586 | 0.67 | GRM2 (1.00) | GRM2GRM3GRM6GRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4418211-A | Preparation of trans-cyclohexane-1,4-disulphonyl urea | AKZONA INCORPORATED (US) | 1983-11-29 | — | — | US | disclosed |
| US-4203916-A | Preparation of trans cyclohexane 1,4 diisocyanate | AKZONA INCORPORATED (US) | 1980-05-20 | — | — | US | disclosed |