Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.47 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.47 |
| ▸ | GRM6 | O15303 | 4/20 | 0.47 |
| ▸ | GRM8 | O00222 | 2/20 | 0.47 |
| ▸ | ARG1 | P05089 | 4/20 | 0.46 |
| ▸ | ARG2 | P78540 | 2/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2939527 | 0.93 | GRM2 (0.46) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL7135246 | 0.93 | GRM2 (0.46) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL28434000 | 0.91 | GRM2 (0.44) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL4961995 | 0.82 | ARG1 (0.35) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL4831107 | 0.77 | SLC6A4 (0.48) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL8443472 | 0.77 | ARG1 (0.46) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL6294440 | 0.77 | ARG1 (0.46) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL4840309 | 0.77 | SLC6A4 (0.48) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL8828098 | 0.77 | SLC6A4 (0.48) | GRM2GRM3GRM6GRM8ARG1 | |
| SCHEMBL6300310 | 0.77 | ARG1 (0.46) | GRM2GRM3GRM6GRM8ARG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754678-B1 | Improvement of physiological tolerance of pharmaceutical active beta-amino acids | BAYER AG (DE) | 2001-01-03 | — | — | EP | claimed |
| US-5935988-A | MIXTURES OF 2-AMINO-4-METHYLENECYCLOPENTANECARBOXYLIC ACID WITH ISOLEUCINE, ALANINE OR PROLINE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | claimed |
| US-5935988-A | MIXTURES OF 2-AMINO-4-METHYLENECYCLOPENTANECARBOXYLIC ACID WITH ISOLEUCINE, ALANINE OR PROLINE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-10 | — | — | US | disclosed |