Phenothiazine

Phenothiazine

SCHEMBL11138570

C=CC(=O)O.C=CC(=O)O.C=CC(=O)O.C=CC(=O)OCCO.OCC(CO)(CO)CO.c1ccc2c(c1)Nc1ccccc1S2

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 2/20 0.44
▸ TSHR P16473 4/20 0.43
▸ MAPK1 P28482 4/20 0.39
▸ HSD17B10 Q99714 3/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ NOX1 Q9Y5S8 8/20 0.39
▸ GAA P10253 6/20 0.39
▸ MAPT P10636 5/20 0.39
▸ MEN1 O00255 4/20 0.39
▸ KMT2A Q03164 4/20 0.39
▸ ALOX15 P16050 3/20 0.39
▸ TDP1 Q9NUW8 3/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ SNCA P37840 2/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ BCHE P06276 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ ADORA3 P0DMS8 1/20 0.39
▸ ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenothiazine SCHEMBL11138730 0.96 TSHR (0.46) THRBTSHRMAPK1HSD17B10KDM4E
Phenothiazine SCHEMBL11134454 0.94 THRB (0.49) THRBTSHRMAPK1HSD17B10KDM4E
Phenothiazine SCHEMBL11136733 0.91 TSHR (0.53) THRBTSHRMAPK1HSD17B10KDM4E
Phenothiazine SCHEMBL157725 0.81 THRB (0.50) THRBTSHRMAPK1HSD17B10KDM4E
Phenothiazine SCHEMBL9483121 0.78 NOX1 (0.63) TSHRMAPK1HSD17B10NOX1GAA
SCHEMBL8710941 0.74 TSHR (0.79) THRBTSHRMAPK1HSD17B10CYP3A4
Acrylic Acid SCHEMBL28805889 0.71 TSHR (0.86) THRBTSHRMAPK1HSD17B10ALOX15
Acrylic Acid SCHEMBL1665306 0.71 TSHR (0.86) THRBTSHRMAPK1HSD17B10ALOX15
Benzene SCHEMBL11756759 0.71 TSHR (0.86) THRBTSHRMAPK1HSD17B10GAA
Acrylic Acid SCHEMBL27491143 0.71 TSHR (0.86) THRBTSHRMAPK1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0020344-B1 PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES GENERAL ELECTRIC COMPANY (US) 1983-10-26 — — EP disclosed
US-4384026-A Photocurable acrylic coated polycarbonate articles GENERAL ELECTRIC COMPANY (US) 1983-05-17 — — US disclosed
EP-0020344-A4 PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES. GEN ELECTRIC (US) 1981-03-27 — — EP disclosed
EP-0020344-A1 PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES. GEN ELECTRIC (US) 1981-01-07 — — EP disclosed
WO-1980000942-A1 PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES GEN ELECTRIC (US) 1980-05-15 — — WO disclosed
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