Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | NOX1 | Q9Y5S8 | 9/20 | 0.47 |
| ▸ | GAA | P10253 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenothiazine SCHEMBL11134454 | 0.96 | THRB (0.49) | TSHRTHRBNOX1GAAMAPT | |
| Phenothiazine SCHEMBL11138730 | 0.94 | TSHR (0.46) | TSHRTHRBNOX1GAAMAPT | |
| Phenothiazine SCHEMBL11138570 | 0.91 | THRB (0.44) | TSHRTHRBNOX1GAAMAPT | |
| Phenothiazine SCHEMBL157725 | 0.86 | THRB (0.50) | TSHRTHRBNOX1GAAMAPT | |
| Phenothiazine SCHEMBL9483121 | 0.77 | NOX1 (0.63) | TSHRNOX1GAAMAPTMEN1 | |
| SCHEMBL29906120 | 0.75 | TSHR (0.61) | TSHRTHRBTDP1CYP3A4HSD17B10 | |
| SCHEMBL301415 | 0.75 | TSHR (0.61) | TSHRTHRBTDP1CYP3A4HSD17B10 | |
| Benzene SCHEMBL11756759 | 0.75 | TSHR (0.86) | TSHRTHRBGAACYP3A4HSD17B10 | |
| SCHEMBL27491142 | 0.74 | TSHR (0.95) | TSHRTHRBACHECYP3A4HSD17B10 | |
| SCHEMBL28222206 | 0.74 | TSHR (0.66) | TSHRTHRBGAACYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020344-B1 | PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES | GENERAL ELECTRIC COMPANY (US) | 1983-10-26 | — | — | EP | disclosed |