SCHEMBL11140752

SCHEMBL11140752

CCCCc1c(Br)ccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 3/20 0.50
GAA P10253 6/20 0.42
TDP1 Q9NUW8 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 8/20 0.42
KDM4E B2RXH2 7/20 0.42
HPGD P15428 3/20 0.42
MC4R P32245 1/20 0.41
HSD17B10 Q99714 4/20 0.39
CYP1A2 P05177 4/20 0.39
TSHR P16473 3/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39
NPC1 O15118 4/20 0.39
HTT P42858 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6684967 0.82 L3MBTL1 (0.41) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL2846325 0.81 NCEH1 (0.52) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL7783948 0.81 NCEH1 (0.45) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL7915017 0.81 HTR2A (0.52) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL6685052 0.81 L3MBTL1 (0.40) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL761100 0.80 NCEH1 (0.51) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL29832803 0.80 NCEH1 (0.51) NCEH1GAATDP1L3MBTL1ALDH1A1
Ammonia Solution, Strong SCHEMBL28807529 0.80 NCEH1 (0.51) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL6680370 0.79 MC4R (0.39) NCEH1GAATDP1L3MBTL1ALDH1A1
SCHEMBL6682145 0.79 MC4R (0.39) NCEH1GAATDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101698796-A Substituted 9,10-dinaphthyl anthracene blue light-emitting organic electro-luminescent material and method for preparing same SHANGHAI TUOYIN DIGITAL TECHNO 2010-04-28 CN claimed
WO-2023214325-A1 PYRAZOLOPYRIMIDINE DERIVATIVES AND USES THEREOF AS TET2 INHIBITORS NOVARTIS AG (CH) 2023-11-09 WO disclosed
CN-101698795-A 9-(6-substituted-2naphthyl-)-10-substitured anthracene derivative blue light organic electroluminescent material and preparation method thereof SHANGHAI TUOYIN DIGITAL TECHNO 2010-04-28 CN disclosed
CN-101698796-A Substituted 9,10-dinaphthyl anthracene blue light-emitting organic electro-luminescent material and method for preparing same SHANGHAI TUOYIN DIGITAL TECHNO 2010-04-28 CN disclosed
US-RE31300-E Process for preparing alkyl- or arylphosphonothioic dihalides STAUFFER CHEMICAL COMPANY (US) 1983-07-05 US disclosed
US-RE30279-E FROM ALKYL OR ARYL HALIDE WITH HALO-SUBSTITUTED TRIVALENT PHOSPHORUS COMPOUNDS AND PHOSPHORUS PENTASULFIDE OR -OXIDE STAUFFER CHEMICAL COMPANY (US) 1980-05-20 US disclosed
US-4076746-A FROM AN ALKYL OR ARYL HALIDE AND PHOSPHORUS SESQUISULFIDE STAUFFER CHEMICAL COMPANY (US) 1978-02-28 US disclosed
US-3968156-A Process for preparing alkyl-or arylphosphonothioic dihalides STAUFFER CHEMICAL COMPANY (US) 1976-07-06 US disclosed