SCHEMBL7915017

SCHEMBL7915017

CCCCc1c2ccccc2cc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
NCEH1 Q6PIU2 1/20 0.48
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 4/20 0.47
HPGD P15428 4/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.46
CYP1A2 P05177 4/20 0.43
LMNA P02545 2/20 0.43
ABCB11 O95342 1/20 0.43
CYP2D6 P10635 1/20 0.43
SCN1A P35498 1/20 0.43
SCN2A Q99250 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
SCN3A Q9NY46 1/20 0.43
HSD17B10 Q99714 3/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL299862 0.94 MAPT (0.53) HTR2AL3MBTL1NCEH1KDM4EALDH1A1
SCHEMBL16267503 0.92 MAPT (0.55) HTR2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL16267023 0.92 MAPT (0.55) HTR2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL16267095 0.92 MAPT (0.55) HTR2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL8379349 0.92 MAPT (0.55) HTR2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL5116260 0.92 MAPT (0.55) HTR2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL7915225 0.87 ALDH1A1 (0.61) HTR2AL3MBTL1NCEH1KDM4EALDH1A1
SCHEMBL7877776 0.87 HTR2A (0.60) HTR2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL7875750 0.87 HTR2A (0.60) HTR2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL16267416 0.86 NPC1 (0.42) HTR2AL3MBTL1NCEH1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112851893-B Irradiation crosslinking polyethylene foam material and preparation method thereof 浙江万里新材料科技有限公司 2022-09-02 CN claimed
CN-112851893-A Irradiation crosslinking polyethylene foam material and preparation method thereof 浙江万里新材料科技有限公司 2021-05-28 CN claimed
US-4523982-A MONOVINYLIDENE DILUENT THE DOW CHEMICAL COMPANY (US) 1985-06-18 US claimed
CN-112851893-B Irradiation crosslinking polyethylene foam material and preparation method thereof 浙江万里新材料科技有限公司 2022-09-02 CN disclosed
CN-112851893-A Irradiation crosslinking polyethylene foam material and preparation method thereof 浙江万里新材料科技有限公司 2021-05-28 CN disclosed
US-20170329220-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE ELEMENT, CURED PRODUCT, SEMICONDUCTOR DEVICE, METHOD FOR FORMING RESIST PATTERN, AND METHOD FOR PRODUCING CIRCUIT SUBSTRATE HITACHI CHEMICAL COMPANY, LTD. (JP) 2017-11-16 US disclosed
CN-106716250-A Photosensitive resin composition, photosensitive element, cured product, semiconductor device, method for forming resist pattern, and method for producing circuit substrate 日立化成株式会社 2017-05-24 CN disclosed
CN-103732650-B Polycarbonate resin, coating liquid containing same, and molded article molded using same 出光兴产株式会社 2016-06-08 CN disclosed
US-9067857-B2 Fluorine-containing aromatic compound and manufacturing method therefor ASAHI GLASS COMPANY, LIMITED (JP) 2015-06-30 US disclosed
US-20140357906-A1 FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR AGC Inc. (JP) 2014-12-04 US disclosed
CN-104114522-A Fluorine-containing aromatic compound and manufacturing method therefor ASAHI GLASS CO LTD 2014-10-22 CN disclosed
EP-0125701-B1 POLYCYCLIC AROMATIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1988-08-03 EP disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
US-4719047-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed
US-4719049-A ANTITUMOR BURROUGHS WELLCOME CO. (US) 1988-01-12 US disclosed
CN-85107531-A Process for producing vinyl chloride polymer 1987-01-21 CN disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
US-4523982-A MONOVINYLIDENE DILUENT THE DOW CHEMICAL COMPANY (US) 1985-06-18 US disclosed
EP-0125701-A2 Polycyclic aromatic compounds THE WELLCOME FOUNDATION LIMITED (GB) 1984-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140357906-A1 FLUORINE-CONTAINING AROMATIC COMPOUND AND MANUFACTURING METHOD THEREFOR AFF1, AFF2, AFF4 HTR2A 3343/4885L3MBTL1 2967/4885NCEH1 541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.