SCHEMBL11140787

SCHEMBL11140787

O=C(O)/C(=C/c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 4/20 0.58
PRMT1 Q99873 1/20 0.56
AKR1C3 P42330 2/20 0.48
AKR1C1 Q04828 1/20 0.47
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
TP53 P04637 1/20 0.41
HTT P42858 1/20 0.41
CYP1B1 Q16678 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL42324 1.00 FBP1 (0.58) FBP1PRMT1AKR1C3AKR1C1CYP3A4
SCHEMBL6382677 1.00 FBP1 (0.58) FBP1PRMT1AKR1C3AKR1C1CYP3A4
SCHEMBL27867388 0.98 FBP1 (0.56) FBP1PRMT1AKR1C3AKR1C1CYP3A4
SCHEMBL27883556 0.98 FBP1 (0.56) FBP1PRMT1AKR1C3AKR1C1CYP3A4
Hydrochloric Acid SCHEMBL4989759 0.98 FBP1 (0.56) FBP1PRMT1AKR1C3AKR1C1CYP3A4
SCHEMBL27897016 0.98 FBP1 (0.56) FBP1PRMT1AKR1C3AKR1C1CYP3A4
SCHEMBL1160336 0.85 FBP1 (0.59) FBP1PRMT1AKR1C3AKR1C1SMN1; SMN2
SCHEMBL6912556 0.85 FBP1 (0.65) FBP1PRMT1AKR1C3AKR1C1SMN1; SMN2
SCHEMBL7299178 0.85 FBP1 (0.65) FBP1PRMT1AKR1C3AKR1C1CYP3A4
SCHEMBL7292016 0.85 FBP1 (0.65) FBP1PRMT1AKR1C3AKR1C1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4411983-A REMOVAL OF NON-IMAGE AREA WITH WATER MISCIBILITY ORGANIC SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1983-10-25 US disclosed
US-3832387-A ALPHA-NITRO-CINNAMIC ACID DERIVATIVES HOFFMANN LA ROCHE 1974-08-27 US disclosed