SCHEMBL11141011

SCHEMBL11141011

CC(c1c[nH]nn1)C(C)(O)c1ccc2ccccc2c1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CASR P41180 1/20 0.38
CYP3A4 P08684 9/20 0.35
CYP2D6 P10635 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
KCNH2 Q12809 1/20 0.34
UGT2B7 P16662 1/20 0.33
PTPN1 P18031 1/20 0.33
CYP17A1 P05093 3/20 0.33
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360757 0.68 CYP3A4 (0.34) CYP3A4CYP17A1
SCHEMBL11221170 0.68
SCHEMBL10984883 0.67 CCR6 (0.35) CYP3A4SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL7132144 0.66 CASR (0.58) CASRCYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL548731 0.66 PTPN1 (0.50) CASRCYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL15301812 0.66
SCHEMBL10872634 0.64 CA1 (0.32) CYP3A4
SCHEMBL6467282 0.63 EPHX1 (0.49) CASRCYP3A4CYP2D6SLC6A2SLC6A4
SCHEMBL10874238 0.63 PDE2A (0.35) SLC6A2SLC6A4SLC6A3KCNH2
SCHEMBL27508894 0.63 CASR (0.51) CASRCYP3A4CYP2D6SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4414210-A 2-Hydroxyarylethyltriazole fungicides ROHM AND HAAS COMPANY (US) 1983-11-08 US disclosed