Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140628 | 0.89 | MEN1 (0.57) | NPSR1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL11143426 | 0.86 | MAPK1 (0.60) | NPSR1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL30734411 | 0.85 | ALDH1A1 (0.63) | NPSR1ALDH1A1KMT2AMAPK1TRPV1 | |
| SCHEMBL11139406 | 0.85 | ALDH1A1 (0.63) | NPSR1ALDH1A1KMT2AMAPK1TRPV1 | |
| SCHEMBL11137902 | 0.84 | KMT2A (0.61) | NPSR1ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL10887336 | 0.82 | MEN1 (0.52) | NPSR1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL10885852 | 0.82 | MEN1 (0.54) | NPSR1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL10890123 | 0.80 | KDM4E (0.53) | NPSR1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL9784527 | 0.80 | MEN1 (0.49) | NPSR1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10889203 | 0.80 | HTT (0.59) | NPSR1ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387106-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-06-07 | — | — | US | claimed |
| US-4387106-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-06-07 | — | — | US | disclosed |