Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145102 | 0.87 | POLB (0.65) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL11143571 | 0.85 | ALOX15 (0.64) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL11141287 | 0.84 | NPSR1 (0.56) | KMT2APOLBMEN1ALDH1A1TSHR | |
| SCHEMBL11140628 | 0.81 | MEN1 (0.57) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL6468205 | 0.81 | KMT2A (0.52) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL10889203 | 0.81 | HTT (0.59) | KMT2AMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL13607121 | 0.80 | NPSR1 (0.74) | KMT2AMEN1ALDH1A1MAPTTP53 | |
| SCHEMBL6468211 | 0.79 | SMN1; SMN2 (0.57) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL29140899 | 0.79 | NPC1 (0.63) | KMT2APOLBMEN1ALDH1A1MAPT | |
| SCHEMBL4935364 | 0.78 | NPSR1 (0.77) | KMT2AMEN1ALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387106-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-06-07 | — | — | US | disclosed |