Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 4/20 | 0.45 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21150753 | 0.85 | GRM4 (0.46) | KHKHTR2CHTR2BHTR2AKMT2A | |
| SCHEMBL11217206 | 0.78 | KHK (0.62) | KHKHTR2CHTR2BHTR2AHTR3E | |
| SCHEMBL9082862 | 0.75 | HTR2C (0.46) | KHKHTR2CHTR2BGAAGFER | |
| SCHEMBL994623 | 0.74 | HTR2C (0.40) | HTR2CHTR2BHTR2A | |
| SCHEMBL10947817 | 0.72 | KHK (0.37) | KHKHTR2CHTR2BHTR2A | |
| SCHEMBL9819250 | 0.71 | CTSG (0.47) | GFERKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11482279 | 0.71 | KHK (0.36) | KHKHTR2CHTR2BHTR2A | |
| SCHEMBL3278976 | 0.70 | HTR2C (0.53) | HTR2CHTR2BGAAGFERHTR2A | |
| SCHEMBL29590229 | 0.70 | GRM4 (0.48) | GAAKMT2AMEN1 | |
| SCHEMBL6366743 | 0.70 | MEN1 (0.61) | GAASIGMAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4414216-A | NEUROLEPTICS | YOSHITOMI PHAMACEUTICAL INDUSTRIES, LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| EP-0068331-A1 | Tetrahydrofuran compounds and analogs thereof | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1983-01-05 | — | — | EP | disclosed |