Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.53 |
| ▸ | HTR2B | P41595 | 5/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279312 | 0.87 | PARP1 (0.49) | HTR2CHTR2BHTR2APARP1NOTUM | |
| SCHEMBL15144720 | 0.82 | HTR2C (0.56) | HTR2CHTR2BHTR2APLATNOS3 | |
| SCHEMBL2709111 | 0.80 | HTR2C (0.77) | HTR2CHTR2BHTR2AALDH1A1NOS3 | |
| Hydrochloric Acid SCHEMBL3947175 | 0.79 | HTR2C (0.75) | HTR2CHTR2BHTR2ANOS3NOS1 | |
| Trifluoroacetic Acid SCHEMBL6246336 | 0.72 | HTR2C (0.64) | HTR2CHTR2BHTR2ATSHRALDH1A1 | |
| SCHEMBL30015409 | 0.72 | HTR2C (0.61) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL2675232 | 0.72 | OPRM1 (0.52) | HTR2CHTR2BTSHRALDH1A1HPGD | |
| SCHEMBL723359 | 0.72 | HTR2C (0.61) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL15202984 | 0.72 | HTR2C (0.77) | HTR2CHTR2BHTR2ANOS3NOS1 | |
| SCHEMBL5871428 | 0.72 | HTR2C (0.83) | HTR2CHTR2BHTR2AALDH1A1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700589-B2 | CGRP antagonists | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2010-04-20 | — | — | US | disclosed |
| US-20070244099-A1 | CGRP Antagonists | RUDOLF KLAUS | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244099-A1 | CGRP Antagonists | CALCRL, OPRL1, CALCA | HTR2C 176/4885HTR2B 65/4885HTR2A 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.