Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 4/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1677378 | 0.89 | HTR7 (0.50) | HTR7ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL12806160 | 0.74 | BCL2 (0.50) | HTR7ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL1113661 | 0.73 | HTR7 (0.46) | HTR7ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL10058377 | 0.73 | BCL2 (0.51) | HTR7ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL15938164 | 0.72 | HTR7 (0.81) | HTR7ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL11212077 | 0.72 | MEN1 (0.52) | HTR7ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL15938285 | 0.72 | HTR7 (0.74) | HTR7ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL376898 | 0.70 | HTR7 (0.60) | HTR7ALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL4296188 | 0.70 | S100B (0.56) | ALDH1A1GAAKDM4EKMT2AMAPT | |
| SCHEMBL20291669 | 0.69 | KDM4E (0.51) | ALDH1A1GAAKDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279174-A2 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Genentech, Inc. (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009143246-A2 | ARYLSULFONAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2009-11-26 | — | — | WO | disclosed |