Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 6/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146884 | 0.89 | MAPT (0.51) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL11153567 | 0.84 | MAPT (0.43) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL11151011 | 0.76 | TDP1 (0.47) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL11145691 | 0.73 | TDP1 (0.43) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL11146366 | 0.71 | TNFRSF1A (0.45) | MAPTALDH1A1TDP1SMN1; SMN2GAA | |
| SCHEMBL14713490 | 0.70 | SIRT2 (0.39) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL11314234 | 0.70 | TNFRSF1A (0.50) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL10134153 | 0.70 | MAPT (0.40) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL11148687 | 0.70 | TNFRSF1A (0.60) | EP300SIRT2SIRT1SIRT5MAPT | |
| SCHEMBL11142094 | 0.70 | MEN1 (0.54) | EP300SIRT2SIRT1SIRT5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |