Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 11/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10134153 | 0.90 | MAPT (0.40) | SIRT2SIRT1SIRT5EP300MAPT | |
| SCHEMBL10134151 | 0.80 | TNFRSF1A (0.49) | SIRT2SIRT1SIRT5EP300MAPT | |
| SCHEMBL12180540 | 0.77 | MAPT (0.42) | SIRT2SIRT1SIRT5EP300MAPT | |
| SCHEMBL26139193 | 0.72 | ENPP3 (0.35) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL14589628 | 0.72 | MAPT (0.65) | MAPTAPPSNCAALDH1A1MEN1 | |
| SCHEMBL2716747 | 0.70 | TNFRSF1A (0.43) | SIRT2SIRT1SIRT5EP300MAPT | |
| SCHEMBL11141964 | 0.70 | EP300 (0.48) | SIRT2SIRT1SIRT5EP300MAPT | |
| SCHEMBL2719600 | 0.70 | CA12 (0.54) | EP300MAPTAPPSNCAALDH1A1 | |
| SCHEMBL26139081 | 0.70 | NEK6 (0.38) | EP300MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL26139244 | 0.70 | ALDH1A1 (0.33) | MAPTALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
| US-20130042918-A1 | OLIGOTHIOPHENES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARIAL ORGANISATION | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130042918-A1 | OLIGOTHIOPHENES | NR0B2, NR2C2, NR1H2 | SIRT2 2511/4885SIRT1 2973/4885SIRT5 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.