Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11146884 | 0.81 | MAPT (0.51) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11153567 | 0.73 | MAPT (0.43) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11285526 | 0.72 | CASP3 (0.35) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11141964 | 0.71 | EP300 (0.48) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL13559205 | 0.70 | MEN1 (0.53) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11282570 | 0.70 | MEN1 (0.39) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11283557 | 0.69 | SLC6A3 (0.40) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11287708 | 0.68 | ALDH1A1 (0.36) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29165195 | 0.68 | TNFRSF1A (0.46) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL29165166 | 0.68 | TNFRSF1A (0.50) | TNFRSF1AMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4389477-A | Photoconductive composition sensitized by a thiobarbituric acid derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |