Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9749675 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP2C19KMT2AMEN1 | |
| SCHEMBL11135656 | 0.83 | CYP1A2 (0.48) | TDP1CYP1A2CYP2C19MAPTCNR2 | |
| SCHEMBL2314388 | 0.78 | MEN1 (0.66) | TDP1CYP1A2FFAR1AKR1B1CYP2D6 | |
| SCHEMBL10916971 | 0.78 | CYP1A2 (0.44) | TDP1CYP1A2FFAR1AKR1B1CYP2D6 | |
| SCHEMBL22129565 | 0.76 | TDP1 (0.61) | TDP1CYP1A2FFAR1AKR1B1CYP2D6 | |
| SCHEMBL30900805 | 0.76 | TDP1 (0.61) | TDP1CYP1A2FFAR1AKR1B1CYP2D6 | |
| SCHEMBL11135874 | 0.76 | SMN1; SMN2 (0.55) | TDP1FFAR1KMT2AMEN1MAPT | |
| SCHEMBL1616841 | 0.75 | TDP1 (0.59) | TDP1CYP1A2FFAR1AKR1B1CYP2D6 | |
| SCHEMBL6842066 | 0.75 | TDP1 (0.59) | TDP1CYP1A2FFAR1AKR1B1CYP2D6 | |
| SCHEMBL3732554 | 0.75 | TDP1 (0.59) | TDP1CYP1A2FFAR1AKR1B1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405810-A | ANTIALLERGENS, BRONCHODILATORS | SCHERING CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |