Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614839 | 0.85 | PPARG (0.43) | CYP1A2CYP2C19FAAH | |
| SCHEMBL11142016 | 0.85 | TDP1 (0.53) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL27926016 | 0.81 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL10916971 | 0.79 | CYP1A2 (0.44) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL9749184 | 0.79 | CYP1A2 (0.57) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL9748786 | 0.76 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL11144744 | 0.73 | CYP1A2 (0.63) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11135874 | 0.73 | SMN1; SMN2 (0.55) | MEN1KMT2A | |
| SCHEMBL4889688 | 0.73 | TDP1 (0.65) | LDHA | |
| SCHEMBL4891945 | 0.73 | PTPN22 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0201071-B1 | 2-SUBSTITUTED-1-NAPHTHOLS AS 5-LIPOXYGENASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-03-04 | — | — | EP | claimed |