Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147497 | 0.92 | ALDH1A1 (0.54) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11146390 | 0.85 | GABRP (0.51) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11842566 | 0.83 | GABRP (0.54) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31541246 | 0.83 | GABRP (0.54) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11146514 | 0.81 | ALDH1A1 (0.54) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27715947 | 0.79 | ALDH1A1 (0.71) | ALDH1A1LMNAGAAMAPTHTT | |
| SCHEMBL11845031 | 0.79 | GABRP (0.43) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11147223 | 0.78 | GABRP (0.44) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11149180 | 0.78 | ALDH1A1 (0.46) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| Fumaric Acid SCHEMBL11146204 | 0.77 | ALDH1A1 (0.50) | ALDH1A1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31237-E | 2-Benzoyl-4-nitroanilides and their use as medicaments | PIERRE FABRE S.A. (FR) | 1983-05-10 | — | — | US | claimed |
| EP-0022017-B1 | DERIVATIVES OF 2-BENZOYL-4-NITRO ANILIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | PIERRE FABRE S.A. (FR) | 1982-05-05 | — | — | EP | claimed |
| US-4289770-A | HYPNOTIC AGENTS FOR TREATMENT OF INSOMNIA | PIERRE FABRE S.A. (FR) | 1981-09-15 | — | — | US | claimed |
| US-RE31237-E | 2-Benzoyl-4-nitroanilides and their use as medicaments | PIERRE FABRE S.A. (FR) | 1983-05-10 | — | — | US | disclosed |
| US-4289770-A | HYPNOTIC AGENTS FOR TREATMENT OF INSOMNIA | PIERRE FABRE S.A. (FR) | 1981-09-15 | — | — | US | disclosed |