Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 5/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.40 |
| ▸ | PLAU | P00749 | 4/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153043 | 0.90 | LMNA (0.46) | CYP1A2LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL11153081 | 0.84 | L3MBTL1 (0.45) | CYP1A2LMNATSHRELANEF2 | |
| SCHEMBL11149094 | 0.83 | CYP1A2 (0.39) | CYP1A2LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL11146591 | 0.81 | LMNA (0.57) | CYP1A2LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL10077048 | 0.78 | ADORA2A (0.54) | CYP1A2LMNATSHRALDH1A1PDE4A | |
| SCHEMBL14909721 | 0.77 | CYP1A2 (0.48) | CYP1A2LMNATSHRALDH1A1PDE4A | |
| SCHEMBL961818 | 0.76 | ELANE (0.52) | CYP1A2LMNATSHRKDM4EALDH1A1 | |
| SCHEMBL11145800 | 0.76 | L3MBTL1 (0.54) | ELANEF2PLAUCTRB1MAPT | |
| SCHEMBL11146995 | 0.76 | MAPT (0.50) | CYP1A2LMNAELANEMAPTKMT2A | |
| SCHEMBL11146570 | 0.75 | LMNA (0.41) | CYP1A2LMNATSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |