Endothall

Endothall

SCHEMBL8466779

O=C(O)C1C2CCC(O2)C1C(=O)O.[KH].[KH].[NaH].[NaH]

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TFPI2 P48307 7/20 0.90
LMNA P02545 2/20 0.90
KDM4E B2RXH2 1/20 0.90
GMNN O75496 1/20 0.90
PMP22 Q01453 1/20 0.90
TP53 P04637 1/20 0.90
TSHR P16473 1/20 0.90
NFKB1 P19838 1/20 0.90
THPO P40225 1/20 0.90
PPM1B O75688 3/20 0.63
PTPN1 P18031 3/20 0.63
PPP1CC P36873 3/20 0.63
PPP1CA P62136 1/20 0.55
PPP5C P53041 2/20 0.53
PPP2CA P67775 1/20 0.53
NPY4R P50391 1/20 0.53
MEN1 O00255 1/20 0.49
ALDH1A1 P00352 1/20 0.49
BLM P54132 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Endothall SCHEMBL11674485 0.97 TFPI2 (0.94) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL4353120 0.97 TFPI2 (0.94) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL11143562 0.97 TFPI2 (0.94) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL9464559 0.95 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL3494764 0.95 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL9464699 0.95 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL8536404 0.95 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL13480837 0.95 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL55158 0.95 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22
Endothall SCHEMBL3495744 0.95 TFPI2 (1.00) TFPI2LMNAKDM4EGMNNPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001382-A COMPRISING COMPLEXES FOR TREATING A POPULATION OF ONE OR MORE AQUATIC ORGANISMS IN A COLUMN OF WATER, THE COMPLEXES COMPRISE AT LEAST ONE SYSTEM WHEREIN THE SYSTEM COMPRISES AT LEAST ONE BIOACTIVE AGENT, A CARRIER, AN ORGANIC PLASTICIZER LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-12-14 US disclosed
US-5902596-A CONTROLLED RELEASE OF BIOACTIVE AGENTS ON PRE-FLOOD OR FLOOD AREA; WATER SOLUBLE, BIODEGRADABLE COATING OF FATTY ALCOHOLS, FATTY ACIDS, FATTY ESTERS OR PHTHALYL ESTERS; MOSQUITO, WEED CONTROL; NO SUPERABSORBENT POLYMERS LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-05-11 US disclosed
US-5885605-A BIOACTIVE AGENT AS A COMPONENT SELECTED FOR TREATING A POPULATION OF AQUATIC ORGANISMS, AT LEAST ONE CARRIER COMPONENT, AND AT LEAST ONE COATING COMPONENT FOR REGULATING THE CONTROLLED RELEASE RATE OF THE BIOACTIVE AGENT IN WATER LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-03-23 US disclosed
US-5858386-A CONTROLLED RELEASE OF BIOACTIVE AGENTS ON DRY PRE-FLOODED LAND; WATER SOLUBLE, BIODEGRADABLE COATING OF FATTY ALCOHOLS, FATTY ACIDS, FATTY ESTERS OR PHTHALYL ESTERS; MOSQUITO, WEED CONTROL; NO SUPERABSORBENT POLYMERS LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-01-12 US disclosed
US-5858384-A Controlled delivery compositions and processes for treating organisms in a column of water or on land LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1999-01-12 US disclosed
US-5846553-A Controlled delivery compositions and processes for treating organisms in a column of water or on land LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1998-12-08 US disclosed
US-5698210-A SUSTAINED RELEASE OF INSECTICIDES, PARASITICIDES, HERBICIDES LEE COUNTY MOSQUITO CONTROL DISTRICT (US) 1997-12-16 US disclosed