Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21400883 | 0.87 | ABCC1 (0.66) | ALOX15TSHRHTTSMN1; SMN2HDAC1 | |
| SCHEMBL11137902 | 0.85 | KMT2A (0.61) | TSHRHTTNPSR1ALDH1A1KMT2A | |
| SCHEMBL11145102 | 0.85 | POLB (0.65) | ALOX15TSHRHTTNPSR1ALDH1A1 | |
| SCHEMBL23200074 | 0.83 | HTT (0.66) | ALOX15TSHRHTTSMN1; SMN2HDAC1 | |
| SCHEMBL21241737 | 0.81 | HDAC6 (0.78) | ALOX15TSHRHTTSMN1; SMN2HDAC1 | |
| SCHEMBL16663612 | 0.80 | HDAC6 (0.77) | TSHRHTTHDAC1HDAC6HDAC3 | |
| SCHEMBL30734411 | 0.80 | ALDH1A1 (0.63) | TSHRNPSR1ALDH1A1KMT2APOLB | |
| SCHEMBL11139406 | 0.80 | ALDH1A1 (0.63) | TSHRNPSR1ALDH1A1KMT2APOLB | |
| SCHEMBL2502378 | 0.80 | HDAC1 (0.81) | ALOX15TSHRHTTSMN1; SMN2HDAC1 | |
| SCHEMBL11003870 | 0.80 | HTT (0.64) | ALOX15TSHRHTTSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387106-A | ANTICHOLESTEROL AGENTS, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-06-07 | — | — | US | disclosed |