Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145638 | 0.92 | ESR1 (0.61) | HSP90AA1HSP90AB1ESR1HDAC8HDAC6 | |
| SCHEMBL11140442 | 0.86 | TP53 (0.66) | ESR1HDAC8HDAC6TP53NPC1 | |
| SCHEMBL11141910 | 0.85 | ESR1 (0.53) | HSP90AA1HSP90AB1ESR1HDAC8HDAC6 | |
| SCHEMBL11136927 | 0.84 | KCNK9 (0.52) | HSP90AA1HSP90AB1ESR1HDAC8HDAC6 | |
| SCHEMBL22746195 | 0.79 | NPC1 (0.63) | HDAC8HDAC6NPC1RAB9AKMT2A | |
| SCHEMBL11133928 | 0.78 | ESR1 (0.51) | ESR1HDAC6TP53NPC1RAB9A | |
| SCHEMBL10242069 | 0.78 | KMT2A (0.71) | HSP90AA1HSP90AB1TP53NPC1RAB9A | |
| SCHEMBL1264161 | 0.77 | MEN1 (0.70) | HSP90AA1HSP90AB1RAB9AKMT2AMEN1 | |
| SCHEMBL17831484 | 0.77 | KCNK3 (0.71) | HSP90AA1HSP90AB1TP53NPC1RAB9A | |
| SCHEMBL13601061 | 0.77 | LMNA (0.72) | HDAC8HDAC6NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4387210-A | Process for producing aromatic polyester amide | MITSUI TOATSU CHEMICAL, INC. (JP) | 1983-06-07 | — | — | US | disclosed |
| EP-0055480-A1 | Process for producing aromatic polyester amide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-07-07 | — | — | EP | disclosed |