Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.70 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11154791 | 0.92 | ALDH1A1 (0.58) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11149089 | 0.90 | ALDH1A1 (0.71) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11151040 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11149202 | 0.89 | ALDH1A1 (0.70) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11148886 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11155056 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11149177 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL11143527 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KDM4ETSHRLMNABLM | |
| Cinoxacin SCHEMBL43770 | 0.83 | KDM4E (1.00) | ALDH1A1KDM4ETSHRLMNABLM | |
| SCHEMBL16450335 | 0.83 | ALDH1A1 (0.81) | ALDH1A1KDM4ETSHRLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | claimed |
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |