Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cinoxacin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinoxacin SCHEMBL29471771 | 1.00 | KDM4E (1.00) | KDM4EALDH1A1LMNATSHRBLM | |
| Cinoxacin SCHEMBL28034322 | 0.99 | KDM4E (0.97) | KDM4EALDH1A1LMNATSHRBLM | |
| Cinoxacin SCHEMBL28034323 | 0.99 | KDM4E (0.97) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11154799 | 0.90 | ALDH1A1 (0.82) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11153077 | 0.90 | ALDH1A1 (0.81) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL16450335 | 0.90 | ALDH1A1 (0.81) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11148183 | 0.88 | ALDH1A1 (0.78) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11669307 | 0.86 | ALDH1A1 (0.76) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11149177 | 0.86 | ALDH1A1 (0.75) | KDM4EALDH1A1LMNATSHRBLM | |
| SCHEMBL11035052 | 0.84 | ALDH1A1 (0.72) | KDM4EALDH1A1LMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11742 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106917-A1 | EDIBLE TRANSMUCOSAL DRUG DELIVERY METHOD USING AN INTERMEDIATE CAPSULE AS A TEMPORARY VESSEL | BioPhysics Pharma, Inc. (US) | 2026-05-21 | — | — | WO | claimed |
| US-12605345-B2 | Transdermal drug delivery system | BioPhysics Pharma, Inc. (US) | 2026-04-21 | — | — | US | claimed |
| EP-4724049-A1 | MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF | Catalent Ontario Limited (CA) | 2026-04-15 | — | — | EP | claimed |
| US-20260033494-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | TEXAS A & M UNIV SYS (US) | 2026-02-05 | — | — | US | claimed |
| US-12458025-B2 | Plant antimicrobial compositions and methods of use thereof | THE TEXAS A & M UNIVERSITY SYSTEM (US) | 2025-11-04 | — | — | US | claimed |
| EP-4626343-A1 | DRUG ELUTING IMPLANTS AND USES THEREOF | MUSC Foundation for Research Development (US) | 2025-10-08 | — | — | EP | claimed |
| US-20250268841-A1 | Trans-Epithelial Membrane Drug Delivery System | Masiz, John J. (US) | 2025-08-28 | — | — | US | claimed |
| EP-4021402-B1 | THIXOTROPIC DELIVERY SYSTEMS | UNIV OF MONTANA (US) | 2025-08-20 | — | — | EP | claimed |
| US-20250228841-A1 | COMPOSITIONS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | APTORUM THERAPEUTICS LTD (HK) | 2025-07-17 | — | — | US | claimed |
| US-12350281-B2 | Long-acting injectable formulations and use thereof | DECHRA VETERINARY PRODUCTS, LLC (US) | 2025-07-08 | — | — | US | claimed |
| WO-1992000090-A1 | COMPOSITION AND TREATMENT WITH BIOLOGICALLY ACTIVE PEPTIDES AND ANTIBIOTICS WHICH INHIBIT DNA GYRASE | MAGAININ PHARMACEUTICALS INC. (US) | 1992-01-09 | — | — | WO | claimed |
| EP-0443381-A1 | Effervescent composition, its production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0405858-A2 | Control of aberrant expression vector accumulation during fermentation procedures | ELI LILLY AND COMPANY (US) | 1991-01-02 | — | — | EP | claimed |
| US-4956460-A | Process for the preparation of 1-alkyl-3-carboxy-4-cinnolones | INDUSTRIA CHIMICA PROFARMACO S.P.A. (IT) | 1990-09-11 | — | — | US | claimed |
| US-4853225-A | Process for implanting a medicament depot | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-08-01 | — | — | US | claimed |
| EP-0293432-A1 | ORGANIC ACID ANHYDRIDE AND PHARMACEUTICAL COMPOSITION ON A PRODRUG BASE | NV GANTAX PHARMACEUTICA (BE) | 1988-12-07 | — | — | EP | claimed |
| WO-1988003020-A1 | ORGANIC ACID ANHYDRIDE AND PHARMACEUTICAL COMPOSITION ON A PRODRUG BASE | NV GANTAX PHARMACEUTICA (BE) | 1988-05-05 | — | — | WO | claimed |
| EP-0152379-A2 | Process for preparing pharmaceutical compositions containing unilamellar liposomes | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | claimed |
| EP-0098577-A2 | Drugs for treating diarrhea caused by infection | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-01-18 | — | — | EP | claimed |
| US-4379929-A | BACTERIOSTATS | ELI LILLY AND COMPANY (US) | 1983-04-12 | — | — | US | claimed |