SCHEMBL111466

SCHEMBL111466

CN(C)c1ccc(C(c2ccc(N(C)C)cc2)c2ccc(Nc3ccccc3)c3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
KMT2A Q03164 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
KDM4E B2RXH2 1/20 0.45
GLA P06280 1/20 0.45
GAA P10253 1/20 0.45
RECQL P46063 1/20 0.45
KDM1A O60341 11/20 0.43
VDR P11473 1/20 0.41
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP13 P45452 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 1/20 0.39
PKM P14618 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL14895224 0.99 MEN1 (0.44) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL224751 0.96 KDM1A (0.46) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL27576852 0.86 MEN1 (0.42) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL3901015 0.85 KDM1A (0.47) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL13679218 0.84 KEAP1 (0.47) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL12206195 0.82 KEAP1 (0.43) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL5009559 0.81 IDO1 (0.45) MEN1MAPTKMT2ATDP1KDM4E
Hydrochloric Acid SCHEMBL14895281 0.80 IDO1 (0.44) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL21165374 0.78 HPGD (0.46) MEN1MAPTKMT2ATDP1KDM4E
SCHEMBL16548057 0.78 KDM1A (0.38) MEN1MAPTKMT2ATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180119059-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US disclosed
US-20180118945-A1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS MILLIKEN & COMPANY 2018-05-03 US disclosed
EP-2424491-B1 FILM FORMER IN HAIR COLOURS HENKEL AG & CO KGAA (DE) 2017-05-24 EP disclosed
EP-1975226-B1 Liquid treatment composition PROCTER & GAMBLE (US) 2013-02-13 EP disclosed
EP-2424491-A2 FILM FORMER IN HAIR DYES Henkel AG & Co. KGaA (DE) 2012-03-07 EP disclosed
EP-1996687-B1 LAUNDRY COMPOSITION PROCTER & GAMBLE (US) 2011-10-26 EP disclosed
US-8003589-B2 Laundry composition THE PROCTER & GAMBLE COMPANY (US) 2011-08-23 US disclosed
US-8003589-B2 Laundry composition THE PROCTER & GAMBLE COMPANY (US) 2011-08-23 US disclosed
EP-1761623-B1 LAUNDRY DETERGENT COMPOSITIONS WITH EFFICIENT HUEING DYE PROCTER & GAMBLE (US) 2010-11-17 EP disclosed
WO-2010124897-A2 FILM FORMER IN HAIR DYES HENKEL AG & CO. KGAA (DE) 2010-11-04 WO disclosed
WO-1999059529-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed
EP-0889719-A1 AGENTS FOR DYING AND DECOLORIZING FIBERS Wella Aktiengesellschaft (DE) 1999-01-13 EP disclosed
EP-0877593-A1 AGENT FOR DYEING AND DECOLORIZING FIBERS Wella Aktiengesellschaft (DE) 1998-11-18 EP disclosed
WO-1998023247-A1 AGENT FOR DYEING AND DECOLORIZING FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1998-06-04 WO disclosed
WO-1998022078-A1 AGENTS FOR DYING AND DECOLORIZING FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1998-05-28 WO disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed