SCHEMBL21165374

SCHEMBL21165374

Cc1ccc(Nc2ccc(C(c3ccc(Nc4ccc(C)cc4)cc3)c3ccc(Nc4ccc(C)cc4)c4ccccc34)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.46
MAPT P10636 5/20 0.42
GAA P10253 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
NPC1 O15118 4/20 0.41
RAB9A P51151 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
KDM4E B2RXH2 2/20 0.41
GLA P06280 1/20 0.41
RECQL P46063 1/20 0.41
KDM1A O60341 1/20 0.40
SNCA P37840 1/20 0.37
KEAP1 Q14145 1/20 0.36
NFE2L2 Q16236 1/20 0.36
POLB P06746 1/20 0.36
MAPK1 P28482 1/20 0.36
GFER P55789 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPY5R Q15761 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165373 0.90 HPGD (0.37) HPGDMAPTGAATDP1NPC1
SCHEMBL12206075 0.86 KDM1A (0.44) HPGDMAPTGAATDP1NPC1
SCHEMBL21165197 0.83 RAPGEF4 (0.42) HPGDMAPTGAATDP1MEN1
SCHEMBL21165036 0.82 RAPGEF4 (0.47) KDM1A
SCHEMBL15960969 0.81 HPGD (0.44) HPGDMAPTGAATDP1NPC1
SCHEMBL21165052 0.81 RAPGEF4 (0.43) MAPTGAATDP1MEN1KMT2A
SCHEMBL17953189 0.80 KDM1A (0.40) HPGDMAPTGAATDP1NPC1
SCHEMBL224751 0.80 KDM1A (0.46) HPGDMAPTGAATDP1NPC1
SCHEMBL15960960 0.79 MMP2 (0.40) HPGDMAPTGAATDP1NPC1
SCHEMBL111466 0.78 MEN1 (0.45) HPGDMAPTGAATDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 HPGD 4062/4885MAPT 1958/4885GAA 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.