Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237882 | 0.89 | KDM4E (0.39) | NAAAEPHX1CACNA1BCYP2C19BCHE | |
| SCHEMBL11207623 | 0.79 | CXCR4 (0.41) | NAAAEPHX1CACNA1BCYP2C19HTT | |
| SCHEMBL11214432 | 0.70 | CXCR4 (0.42) | BCHEHTTKDM4E | |
| SCHEMBL11211821 | 0.70 | KDM4E (0.40) | BCHEHTTTSHRKDM4E | |
| SCHEMBL7109105 | 0.69 | CACNA1B (0.61) | EPHX1CACNA1BCYP2C19 | |
| SCHEMBL29400846 | 0.69 | CACNA1B (0.61) | EPHX1CACNA1BCYP2C19 | |
| SCHEMBL18460226 | 0.69 | CACNA1B (0.61) | EPHX1CACNA1BCYP2C19 | |
| SCHEMBL14017648 | 0.69 | CACNA1B (0.61) | EPHX1CACNA1BCYP2C19 | |
| SCHEMBL11148996 | 0.69 | HTT (0.47) | HTTTSHRKDM4ENPC1 | |
| SCHEMBL9805775 | 0.69 | KDM4E (0.46) | HTTTSHRKDM4ENPC1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022059-B1 | N-SUBSTITUTED ESTERS OF ASPARTIC ACID, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1983-08-17 | — | — | EP | claimed |
| US-4326069-A | CURING AGENTS FOR POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1982-04-20 | — | — | US | claimed |
| US-4326069-A | CURING AGENTS FOR POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |