SCHEMBL11207623

SCHEMBL11207623

O=C(C[C@H](NCCCNC1CCCCC1)C(=O)O)OC1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 2/20 0.41
EPHX1 P07099 2/20 0.39
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 3/20 0.38
NAAA Q02083 2/20 0.38
SIGMAR1 Q99720 1/20 0.37
CACNA1B Q00975 3/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
TAAR1 Q96RJ0 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11214432 0.88 CXCR4 (0.42) CXCR4ALDH1A1SIGMAR1TAAR1HTT
SCHEMBL11211821 0.85 KDM4E (0.40) CXCR4ALDH1A1SIGMAR1HTTSMN1; SMN2
SCHEMBL11205755 0.85 CXCR4 (0.39) CXCR4ALDH1A1SIGMAR1TAAR1HTT
SCHEMBL11237882 0.82 KDM4E (0.39) EPHX1CYP2C19ALDH1A1NAAACACNA1B
SCHEMBL11147161 0.79 NAAA (0.39) EPHX1CYP2C19NAAACACNA1BHTT
SCHEMBL29400846 0.71 CACNA1B (0.61) EPHX1CYP2C19CACNA1BHDAC4HDAC1
SCHEMBL7109105 0.71 CACNA1B (0.61) EPHX1CYP2C19CACNA1BHDAC4HDAC1
SCHEMBL18460226 0.71 CACNA1B (0.61) EPHX1CYP2C19CACNA1BHDAC4HDAC1
SCHEMBL14017648 0.71 CACNA1B (0.61) EPHX1CYP2C19CACNA1BHDAC4HDAC1
SCHEMBL20758863 0.70 EPHX1 (0.41) CXCR4EPHX1ALDH1A1HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0018948-B1 N-SUBSTITUTED DERIVATIVES OF ASPARTIC ACID, PROCESS FOR THEIR PREPARATION, THEIR USE AND EPOXY RESINS PRODUCED WITH THEIR AID CIBA-GEIGY AG (CH) 1983-07-13 EP claimed
US-4284755-A REACTING A MALEIC MONOESTER AND A DIAMINE CIBA-GEIGY CORPORATION (US) 1981-08-18 US claimed
US-4284755-A REACTING A MALEIC MONOESTER AND A DIAMINE CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed