Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147161 | 0.89 | NAAA (0.39) | KDM4ENPC1NAAAEPHX1CACNA1B | |
| SCHEMBL11207623 | 0.82 | CXCR4 (0.41) | KDM4ENAAAEPHX1CACNA1BCYP2C19 | |
| SCHEMBL9805775 | 0.80 | KDM4E (0.46) | KDM4ENPC1HTTTSHR | |
| SCHEMBL9805779 | 0.80 | KDM4E (0.46) | KDM4ENPC1HTTTSHR | |
| SCHEMBL11151811 | 0.76 | KDM4E (0.43) | KDM4ENPC1HTTTSHRLMNA | |
| SCHEMBL11234189 | 0.76 | KDM4E (0.43) | KDM4ENPC1HTTTSHR | |
| SCHEMBL6947286 | 0.75 | KDM4E (0.48) | KDM4ENPC1TSHR | |
| SCHEMBL6947280 | 0.75 | KDM4E (0.48) | KDM4ENPC1TSHR | |
| SCHEMBL11152622 | 0.73 | DNM1 (0.42) | KDM4ENPC1NAAATSHRALDH1A1 | |
| SCHEMBL11214432 | 0.73 | CXCR4 (0.42) | KDM4EHTTBCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326069-A | CURING AGENTS FOR POLYEPOXIDES | CIBA-GEIGY CORPORATION (US) | 1982-04-20 | — | — | US | disclosed |