Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364394 | 0.90 | LMNA (0.68) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7059111 | 0.87 | LMNA (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL4029442 | 0.87 | LMNA (0.48) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19119173 | 0.87 | TSHR (0.50) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL28646955 | 0.87 | TSHR (0.50) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL7214781 | 0.85 | SMN1; SMN2 (0.45) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10842676 | 0.82 | TSHR (0.50) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL9851115 | 0.82 | TSHR (0.50) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10841539 | 0.82 | TSHR (0.50) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL10401685 | 0.82 | TSHR (0.50) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4416876-A | PHARMACEUTICAL AGENTS | SANDOZ, INC. (US) | 1983-11-22 | — | — | US | disclosed |